The Fragile X Alliance Inc is a non-profit organisation whose mission statement is to promote education and research into fragile X syndrome, as well as disseminate information and new findings about fragile X syndrome.
Specifically, FXA Inc offer clinical services and educational resources. In addition to this, we are strongly involved in research projects aimed at improving care and understanding of FXS.
More information about us
News and Events
‘‘It’s Something I Need to Consider” Decisions About Carrier Screening for Fragile X Syndrome in a Population of Non-Pregnant Women – Archibald AD, Jaques AM, Wake S, Collins VR, Cohen J, Metcalfe SA. 2009 – Am J Med Genet Part A 149A:2731–2738 Download – PDF...read more
Dear all, I hope everyone is doing well. In light of recent reviews of our clinic operation, we have made a few changes to our clinic preparation. Please note the following changes: - instead of booking clinics prior to other requirements, we will now be requiring...read more
Fragile X Associated Disorders
Fragile X Syndrome
Fragile X Syndrome (FXS) is a genetic disorder caused by a mutation (a change in the DNA structure) in the X chromosome. It is the most common known cause of inherited developmental disability worldwide. One in 3,600 males and one in 4-6,000 females are affected. One in 150 females carry the premutation and will pass the gene on to 50% of their offspring, male or female, any of whom may be affected.
Fragile X-associated tremor/ataxia syndrome (FXTAS), a condition which affects balance, tremor and memory in some older male gene carriers.
Fragile X-associated primary ovarian insufficiency (FXPOI), a problem with ovarian function which can lead to infertility and early menopause in some female gene carriers.